Loading, please wait...

Loading, please wait.



9569 - 13299
Mus Musculus - Deletions

Deletion length: 3729 bp

Breakpoint flanking sequences
more information in Documentation - Flanking regions


9569
5fl vs 3del
Homology length: 15 bp

Deleted region


13299
CAGAAAAAGCAAATCCATAT 5'Breakpoint GAATGCGGATTCGACCCTAC (...) TAAATAAAGCAAATCCATAT 3'Breakpoint TCATCCTTCTCAACTTTACT
5fl vs 3fl
Homology length: 1 bp

CAGAAAAAGCAAATCCATAT 5'Breakpoint GAATGCGGATTCGACCCTAC (...) TAAATAAAGCAAATCCATAT 3'Breakpoint TCATCCTTCTCAACTTTACT




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [2] Tanhauser, S. M., Laipis, P. J., Multiple deletions are detectable in mitochondrial DNA of aging mice.The Journal of Biological Chemistry. 1995. 270(42): p. 24769-75.

 [5] Wang, E., et al., The rate of mitochondrial mutagenesis is faster in mice than humans.Mutation Research. 1997. 377(2): p. 157-66.

 [18] Brossas, J. Y., et al., Multiple deletions in mitochondrial DNA are present in senescent mouse brain.Biochemical and Biophysical Research Communications. 1994. 202(2): p. 654-9.

 [21] Zeng, Z., et al., Mitochondrial DNA deletions are associated with ischemia and aging in Balb/c mouse brain.Journal of Cellular Biochemistry. 1999. 73(4): p. 545-53.