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8637 - 16084
Homo sapiens - Deletions

Deletion length: 7446 bp

Does not remove any origin of replication
Inside the major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


8637
5fl vs 3del
Homology length: 1 bp

Deleted region


16084
TCCCCACCTCCAAATATCTC 5'Breakpoint ATCAACAACCGACTAATCAC (...) TGACTCACCCATCAACAACC 3'Breakpoint GCTATGTATTTCGTACATTA
5del vs 3del
Homology length: 10 bp

TCCCCACCTCCAAATATCTC 5'Breakpoint ATCAACAACCGACTAATCAC (...) TGACTCACCCATCAACAACC 3'Breakpoint GCTATGTATTTCGTACATTA




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [147] Remes, A.M., et al., Mitochondrial DNA deletions in dilated cardiomyopathy: a clinical study employing endomyocardial sampling. Journal of the American College of Cardiology. 1994. 23(4): p. 935-42.

 [323] Kim, U. K., et al., Analysis of mitochondrial DNA deletions in four chambers of failing human hearts: hemodynamic stess, age, and disease are important factors. Basic Research in Cardiology. 2000. 95(2): p. 163-71.