8437 - 14068 Homo sapiens - Duplications Duplication length: 10939 bp Duplicated region: 14068:8437 Partially duplicated molecule length: 27508 bp Duplicates OL and OH Duplicating part of minor and major arcs	Breakpoint flanking sequences more information in Documentation - Flanking regions
	8437 5fl vs 3del Homology length: 8 bp Non-duplicated region 14068 TTACACTATTCCTCATCACC ├ 5'Breakpoint ┤ CAACTAAAAATATTAAACAC (...) TCTCCACCTCCATCATCACC ├ 3'Breakpoint ┤ TCAACCCAAAAAGGCATAAT 5del vs 3del Homology length: 1 bp TTACACTATTCCTCATCACC ├ 5'Breakpoint ┤ CAACTAAAAATATTAAACAC (...) TCTCCACCTCCATCATCACC ├ 3'Breakpoint ┤ TCAACCCAAAAAGGCATAAT

Two-dimensional scatterplot showing the location of the selected duplication (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the duplicated region (black bar).
Length distribution of the duplicated region in the selected duplication (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [26] Krauch, G., et al., Pearson Marrow-Pancreas syndrome with worsening cardiac function caused by pleotropic rearrangement of mitochondrial DNA. American Journal of Medical Genetics. 2002. 110: p. 57-61.