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5330 - 16077
Homo sapiens - Deletions

Deletion length: 10746 bp

Removes OL
Removing part of minor and major arcs



Breakpoint flanking sequences
more information in Documentation - Flanking regions


5330
5fl vs 3del
Homology length: 2 bp

Deleted region


16077
TCATAGCCACCATCACCCTC 5'Breakpoint CTTAACCTCTACTTCTACCT (...) CAAGTATTGACTCACCCATC 3'Breakpoint AACAACCGCTATGTATTTCG
5del vs 3del
Homology length: 1 bp

TCATAGCCACCATCACCCTC 5'Breakpoint CTTAACCTCTACTTCTACCT (...) CAAGTATTGACTCACCCATC 3'Breakpoint AACAACCGCTATGTATTTCG




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [23] Kajander, O.A., et al., Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states. Human Molecular Genetics. 2000. 9(19): p. 2821-35.

 [25] Samuels, D.C., E.A. Schon, and P.F. Chinnery, Two direct repeats cause most human mtDNA deletions. Trends in Genetics. 2004. 20(9): p. 393-8.