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3263 - 16072
Homo sapiens - Deletions

Deletion length: 12808 bp

Removes OL
Removing part of minor and major arcs



Breakpoint flanking sequences
more information in Documentation - Flanking regions


3263
5fl vs 3del
Homology length: 2 bp

Deleted region


16072
GCCCGGTAATCGCATAAAAC 5'Breakpoint TTAAAACTTTACAGTCAGAG (...) CCACCCAAGTATTGACTCAC 3'Breakpoint CCATCAACAACCGCTATGTA
5fl vs 3fl
Homology length: 1 bp

GCCCGGTAATCGCATAAAAC 5'Breakpoint TTAAAACTTTACAGTCAGAG (...) CCACCCAAGTATTGACTCAC 3'Breakpoint CCATCAACAACCGCTATGTA




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [6] Bodyak, N.D., et al., Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues. Human Molecular Genetics. 2001. 10(1): p. 17-24.

 [23] Kajander, O.A., et al., Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states. Human Molecular Genetics. 2000. 9(19): p. 2821-35.