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307 - 16189
Homo sapiens - Duplications

Duplication length: 688 bp
Duplicated region: 16189:307

Partially duplicated molecule length: 17257 bp

Does not duplicate any origin of replication
Duplicating part of major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


307
5fl vs 3del
Homology length: 8 bp

Non-duplicated region


16189
AAAATTTCCACCAAACCCCC 5'Breakpoint CCTCCCCCGCTTCTGGCCAC (...) CAATCCACATCAAAACCCCC 3'Breakpoint TCCCCATGCTTACAAGCAAG
5del vs 3del
Homology length: 2 bp

AAAATTTCCACCAAACCCCC 5'Breakpoint CCTCCCCCGCTTCTGGCCAC (...) CAATCCACATCAAAACCCCC 3'Breakpoint TCCCCATGCTTACAAGCAAG




Two-dimensional scatterplot showing the location of the selected duplication (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the duplicated region (black bar).
Length distribution of the duplicated region in the selected duplication (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [31] Wei, Y-H., et al., Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human ageing process.Annals of New York Academy of Sciences. 1996. 786: p. 82-101.