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5328 - 16076
Homo sapiens - Deletions

Deletion length: 10747 bp

Removes OL
Removing part of minor and major arcs



Breakpoint flanking sequences
more information in Documentation - Flanking regions


5328
5fl vs 3fl
Homology length: 1 bp

Deleted region


16076
CATCATAGCCACCATCACCC 5'Breakpoint TCCTTAACCTCTACTTCTAC (...) CCAAGTATTGACTCACCCAT 3'Breakpoint CAACAACCGCTATGTATTTC
5del vs 3del
Homology length: 1 bp

CATCATAGCCACCATCACCC 5'Breakpoint TCCTTAACCTCTACTTCTAC (...) CCAAGTATTGACTCACCCAT 3'Breakpoint CAACAACCGCTATGTATTTC




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [23] Kajander, O.A., et al., Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states. Human Molecular Genetics. 2000. 9(19): p. 2821-35.

 [25] Samuels, D.C., E.A. Schon, and P.F. Chinnery, Two direct repeats cause most human mtDNA deletions. Trends in Genetics. 2004. 20(9): p. 393-8.