Loading, please wait...

Loading, please wait.



15643 - 15665
Homo sapiens - Deletions

Deletion length: 21 bp

Does not remove any origin of replication
Inside the major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


15643
5fl vs 3del
Homology length: 2 bp

Deleted region


15665
CCCTATTACTATCCATCCTC 5'Breakpoint ATCCTAGCAATAATCCCCAT (...) TCCTAGCAATAATCCCCATC 3'Breakpoint CTCCATATATCCAAACAACA
5fl vs 3fl
Homology length: 3 bp

CCCTATTACTATCCATCCTC 5'Breakpoint ATCCTAGCAATAATCCCCAT (...) TCCTAGCAATAATCCCCATC 3'Breakpoint CTCCATATATCCAAACAACA
5del vs 3del
Homology length: 3 bp

CCCTATTACTATCCATCCTC 5'Breakpoint ATCCTAGCAATAATCCCCAT (...) TCCTAGCAATAATCCCCATC 3'Breakpoint CTCCATATATCCAAACAACA




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [51] Dasgupta, S., et al., Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer. Cancer Research. 2008. 68(3): p. 700-6.

 [52] Fliss, M.S., et al., Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science. 2000. 287(5460): p. 2017-9.