11262 - 15362 Homo sapiens - Deletions Deletion length: 4099 bp Does not remove any origin of replication Inside the major arc

Breakpoint flanking sequences more information in Documentation - Flanking regions

11262 5fl vs 3del Homology length: 3 bp Deleted region 15362 ATCGCACTAATTTACACTCA ├ 5'Breakpoint ┤ CAACACCCTAGGCTCACTAA (...) TCTTGCACGAAACGGGATCA ├ 3'Breakpoint ┤ AACAACCCCCTAGGAATCAC 5fl vs 3fl Homology length: 1 bp ATCGCACTAATTTACACTCA ├ 5'Breakpoint ┤ CAACACCCTAGGCTCACTAA (...) TCTTGCACGAAACGGGATCA ├ 3'Breakpoint ┤ AACAACCCCCTAGGAATCAC 5del vs 3del Homology length: 2 bp ATCGCACTAATTTACACTCA ├ 5'Breakpoint ┤ CAACACCCTAGGCTCACTAA (...) TCTTGCACGAAACGGGATCA ├ 3'Breakpoint ┤ AACAACCCCCTAGGAATCAC

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [322] Sadikovic, B., et al., Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes. Plos one. 2010. 5(12): p. e15687.