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8968 - 12890
Mus Musculus - Deletions

Deletion length: 3921 bp

Breakpoint flanking sequences
more information in Documentation - Flanking regions


8968
5fl vs 3del
Homology length: 8 bp

Deleted region


12890
TGCTGACCTCCAACAGGAAT 5'Breakpoint TTCACCACTTAACCCTCTAG (...) AGCCTCGCCCTCACAGGAAT 3'Breakpoint ACCATTCCTAACAGGGTTCT
5del vs 3del
Homology length: 1 bp

TGCTGACCTCCAACAGGAAT 5'Breakpoint TTCACCACTTAACCCTCTAG (...) AGCCTCGCCCTCACAGGAAT 3'Breakpoint ACCATTCCTAACAGGGTTCT




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [8] Fujibayashi, Y., et al., Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress barin.Neuroscience Letters. 1998. 254(2): p. 109-12.

 [14] Vermulst, M., et al., DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.Nature Genetics. 2008. 40(4): p. 392-4.