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8908 - 13051
Mus Musculus - Deletions

Deletion length: 4142 bp

Breakpoint flanking sequences
more information in Documentation - Flanking regions


8908
5fl vs 3del
Homology length: 5 bp

Deleted region


13051
GCAGGATTCTTCTGAGCGTT 5'Breakpoint CTATCATTCTAGCCTCGTAC (...) AACAATAACAAAACCGCGTT 3'Breakpoint TTCCCCCCCTAATCTCCATT
5fl vs 3fl
Homology length: 2 bp

GCAGGATTCTTCTGAGCGTT 5'Breakpoint CTATCATTCTAGCCTCGTAC (...) AACAATAACAAAACCGCGTT 3'Breakpoint TTCCCCCCCTAATCTCCATT




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [14] Vermulst, M., et al., DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.Nature Genetics. 2008. 40(4): p. 392-4.