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8877 - 12791
Mus Musculus - Deletions

Deletion length: 3913 bp

Breakpoint flanking sequences
more information in Documentation - Flanking regions


8877
5fl vs 3fl
Homology length: 1 bp

Deleted region


12791
TCTATTCATCGTCTCGGAAG 5'Breakpoint TATTTTTCTTTGCAGGATTC (...) GGCTCAATCATTCATAGCCT 3'Breakpoint GGCAGACGAACAAGACATCC
5del vs 3del
Homology length: 1 bp

TCTATTCATCGTCTCGGAAG 5'Breakpoint TATTTTTCTTTGCAGGATTC (...) GGCTCAATCATTCATAGCCT 3'Breakpoint GGCAGACGAACAAGACATCC




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [14] Vermulst, M., et al., DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.Nature Genetics. 2008. 40(4): p. 392-4.