8476 - 14812 Homo sapiens - Deletions Deletion length: 6335 bp Does not remove any origin of replication Inside the major arc	Breakpoint flanking sequences more information in Documentation - Flanking regions
	8476 5fl vs 3del Homology length: 7 bp Deleted region 14812 CAAACTACCACCTACCTCCC ├ 5'Breakpoint ┤ TCACCAAAGCCCATAAAAAT (...) CACTCATTCATCGACCTCCC ├ 3'Breakpoint ┤ CACCCCATCCAACATCTCCG 5fl vs 3fl Homology length: 1 bp CAAACTACCACCTACCTCCC ├ 5'Breakpoint ┤ TCACCAAAGCCCATAAAAAT (...) CACTCATTCATCGACCTCCC ├ 3'Breakpoint ┤ CACCCCATCCAACATCTCCG

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

Present in:
KSS
Aged tissues

References

 [18] Ferlin, T., et al., Detection of mitochondrial DNA deletions by a screening procedure using the polymerase chain reaction. Molecular and Cellular Biochemistry. 1997. 174(1-2): p. 221-225.

 [44] Tengan, C.H., et al., Frequency of duplications in the D-loop in patients with mitochondrial DNA deletions. Biochimica Et Biophysica Acta. 2002. 1588(1): p. 65-70.

 [163] Zhang, C., et al., Multiple Mitochondrial-DNA Deletions in an Elderly Human Individual. FEBS Letters. 1992. 297(1-2): p. 34-38.