8312 - 13667 Homo sapiens - Deletions Deletion length: 5354 bp Does not remove any origin of replication Inside the major arc	Breakpoint flanking sequences more information in Documentation - Flanking regions
	8312 5fl vs 3del Homology length: 3 bp Deleted region 13667 CCCACTGTAAAGCTAACTTA ├ 5'Breakpoint ┤ GCATTAACCTTTTAAGTTAA (...) CCCCACCCTTACTAACATTA ├ 3'Breakpoint ┤ ACGAAAATAACCCCACCCTA 5fl vs 3fl Homology length: 1 bp CCCACTGTAAAGCTAACTTA ├ 5'Breakpoint ┤ GCATTAACCTTTTAAGTTAA (...) CCCCACCCTTACTAACATTA ├ 3'Breakpoint ┤ ACGAAAATAACCCCACCCTA

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

Present in:
Controls
Profound presbycusis

References

 [148] Markaryan, A., E.G. Nelson, and R. Hinojosa, Detection of mitochondrial DNA deletions in the cochlea and its structural elements from archival human temporal bone tissue. Mutation Research. 2008. 640(1-2): p. 38-45.