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8058 - 12215
Homo sapiens - Deletions

Deletion length: 4156 bp

Does not remove any origin of replication
Inside the major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


8058
5fl vs 3fl
Homology length: 8 bp

Deleted region


12215
ATAATAATTACATCACAAGA 5'Breakpoint CGTCTTGCACTCATGAGCTG (...) CCCTTATTTACCGAGAAAGC 3'Breakpoint TCACAAGAACTGCTAACTCA
5del vs 3del
Homology length: 1 bp

ATAATAATTACATCACAAGA 5'Breakpoint CGTCTTGCACTCATGAGCTG (...) CCCTTATTTACCGAGAAAGC 3'Breakpoint TCACAAGAACTGCTAACTCA




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [159] Lebrecht, D., et al., Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin. The Journal of Pathology. 2005. 207(4): p. 436-44.