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7329 - 14531
Homo sapiens - Deletions

Deletion length: 7201 bp

Does not remove any origin of replication
Inside the major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


7329
5fl vs 3del
Homology length: 3 bp

Deleted region


14531
TTTCATGATTTGAGAAGCCT 5'Breakpoint TCGCTTCGAAGCGAAAAGTC (...) CTATTAAACCCATATAACCT 3'Breakpoint CCCCCAAAATTCAGAATAAT
5del vs 3del
Homology length: 1 bp

TTTCATGATTTGAGAAGCCT 5'Breakpoint TCGCTTCGAAGCGAAAAGTC (...) CTATTAAACCCATATAACCT 3'Breakpoint CCCCCAAAATTCAGAATAAT




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [286] Wanrooij, S., et al., Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA. Nucleic Acids Research. 2004. 32(10): p. 3053-64.