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6130 - 15056
Homo sapiens - Duplications

Duplication length: 7644 bp
Duplicated region: 15056:6130

Partially duplicated molecule length: 24213 bp

Duplicates OL and OH
Duplicating part of minor and major arcs

Breakpoint flanking sequences
more information in Documentation - Flanking regions
6130 Non-duplicated region 15056

Two-dimensional scatterplot showing the location of the selected duplication (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the duplicated region (black bar).
Length distribution of the duplicated region in the selected duplication (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.
Present in:
Diabetes mellitus


 [14] Poulton, J., et al., Duplications of mitochondrial DNA: Implications in pathogenesis. Journal of Inherited Metabolism Disorders. 1992. 15: p. 487-498.

 [15] Marchington, D. R., et al., Evidence from human oocytes for a genetic bottleneck in an mtDNA disease. American Journal of Human Genetics. 1998. 63: p. 769-775.

 [24] Poulton, J., et al., Families of mtDNA re-arrangements can be detected in patients with mtDNA deletions: duplications may be a transient intermediate form. Human Molecular Genetics. 1993. 2(1): p. 23-30.