5173 - 15607 Homo sapiens - Deletions Deletion length: 10433 bp Removes OL Removing part of minor and major arcs

Breakpoint flanking sequences more information in Documentation - Flanking regions

5173 5fl vs 3del Homology length: 2 bp Deleted region 15607 CTACTATCTCGCACCTGAAA ├ 5'Breakpoint ┤ CAAGCTAACATGACTAACAC (...) CTCCGATCCGTCCCTAACAA ├ 3'Breakpoint ┤ ACTAGGAGGCGTCCTTGCCC 5fl vs 3fl Homology length: 1 bp CTACTATCTCGCACCTGAAA ├ 5'Breakpoint ┤ CAAGCTAACATGACTAACAC (...) CTCCGATCCGTCCCTAACAA ├ 3'Breakpoint ┤ ACTAGGAGGCGTCCTTGCCC 5del vs 3del Homology length: 3 bp CTACTATCTCGCACCTGAAA ├ 5'Breakpoint ┤ CAAGCTAACATGACTAACAC (...) CTCCGATCCGTCCCTAACAA ├ 3'Breakpoint ┤ ACTAGGAGGCGTCCTTGCCC

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [290] Nicholas, A., et al., On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR. Experimental Neurology. 2009. 218(2): p. 316-9.