3020 - 15383 Mus Musculus - Deletions Deletion length: 12362 bp

Breakpoint flanking sequences more information in Documentation - Flanking regions

3020 5fl vs 3del Homology length: 4 bp Deleted region 15383 GTCTATGAGTTCCCCTACCA ├ 5'Breakpoint ┤ ATACCACACCCATTAATTAA (...) GAAGGAGCTACTCCCCACCA ├ 3'Breakpoint ┤ CCAGCACCCAAAGCTGGTAT 5fl vs 3fl Homology length: 3 bp GTCTATGAGTTCCCCTACCA ├ 5'Breakpoint ┤ ATACCACACCCATTAATTAA (...) GAAGGAGCTACTCCCCACCA ├ 3'Breakpoint ┤ CCAGCACCCAAAGCTGGTAT 5del vs 3del Homology length: 1 bp GTCTATGAGTTCCCCTACCA ├ 5'Breakpoint ┤ ATACCACACCCATTAATTAA (...) GAAGGAGCTACTCCCCACCA ├ 3'Breakpoint ┤ CCAGCACCCAAAGCTGGTAT

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [12] Tyynismaa, H., et al., Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice.PNAS. 2005. 102(49): p. 17687-92.