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16164 - 16319
Homo sapiens - Deletions

Deletion length: 154 bp

Does not remove any origin of replication
Inside the major arc



Breakpoint flanking sequences
more information in Documentation - Flanking regions


16164
5fl vs 3del
Homology length: 11 bp

Deleted region


16319
GACCACCTGTAGTACATAAA 5'Breakpoint AACCCAATCCACATCAAAAC (...) AACAGTACATAGTACATAAA 3'Breakpoint GCCATTTACCGTACATAGCA
5del vs 3del
Homology length: 2 bp

GACCACCTGTAGTACATAAA 5'Breakpoint AACCCAATCCACATCAAAAC (...) AACAGTACATAGTACATAAA 3'Breakpoint GCCATTTACCGTACATAGCA




Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.

Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [9] Bua, E., et al., Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers. American Journal of Human Genetics. 2006. 79(3): p. 469-80.

 [281] Behar, D.M., et al., A Novel 154-bp Deletion in the Human Mitochondrial DNA Control Region in Healthy Individuals. Human Mutation. 2008. 29(12): p. 1387-1391.